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Cytotoxic Effect on Cancerous Cell Lines by Biologically Synthesized Silver Nanoparticles BABT
Kulandaivelu,Balaji; Gothandam,K M.
The biosynthesis of nanoparticles has been proposed as an environmental friendly and cost effective alternative to chemical and physical methods. Silver nanoparticles are biologically synthesized and characterized were used in the study. The invitro cytotoxic effect of biologically synthesized silver nanoparticles against MCF-7 cancer cell lines were assessed. The cytotoxic effects of the silver nanoparticles could significantly inhibited MCF-7 cancer cell lines proliferation in a time and concentration-dependent manner by MTT assay. Acridine orange, ethidium bromide (AO/EB) dual staining, caspase-3 and DNA fragmentation assays were carried out using various concentrations of silver nanoparticles ranging from 1 to 100 μg/mL. At 100 μg/mL concentration, the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Silver nanoparticle; Nanotechnology; Nanobiotechnology; Nanoparticle; Cytotoxicity.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100307
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Nanoinformatics: an emerging area of information technology at the intersection of bioinformatics, computational chemistry and nanobiotechnology Biol. Res.
González-Nilo,Fernando; Pérez-Acle,Tomás; Guínez-Molinos,Sergio; Geraldo,Daniela A; Sandoval,Claudia; Yévenes,Alejandro; Santos,Leonardo S; Laurie,V. Felipe; Mendoza,Hegaly; Cachau,Raúl E.
After the progress made during the genomics era, bioinformatics was tasked with supporting the flow of information generated by nanobiotechnology efforts. This challenge requires adapting classical bioinformatic and computational chemistry tools to store, standardize, analyze, and visualize nanobiotechnological information. Thus, old and new bioinformatic and computational chemistry tools have been merged into a new sub-discipline: nanoinformatics. This review takes a second look at the development of this new and exciting area as seen from the perspective of the evolution of nanobiotechnology applied to the life sciences. The knowledge obtained at the nano-scale level implies answers to new questions and the development of new concepts in different...
Tipo: Journal article Palavras-chave: Bioinformatics; Molecular simulation; Nanobiotechnology; Nanoinformatics; Nanomedicine.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000100006
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Phytofabrication of silver nanoparticles using Myriostachya wightiana as a novel bioresource, and evaluation of their biological activities BABT
Vadlapudi,Varahalarao; Amanchy,Ramars.
ABSTRACT Nanobiotechnology deals with the properties of nanomaterials and their potential uses. Here we report for the first time novel, cost-effective and eco-friendly method for the rapid green synthesis of silver nanoparticles (AgNPs) using leaf extracts of Myriostachya wightiana. The growth of silver nanoparticles was monitored by UV-vis spectroscopy complemented by Zeta potential, dynamic light scattering technique (DLS), Fourier-transform infrared spectroscopy (FTIR), Transmission electron microscope (TEM) and X-ray diffraction (XRD). The surface plasmon resonance (SPR) band found at 434 nm confirmed the reduction of AgNO3 to AgNPs. TEM micrographs revealed that AgNPs are irregular in shape with the size range from 15-65 nm. The functional groups...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nanobiotechnology; Myriostachya wightiana; Tribolium castaneum; Xanthomonas campestris.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100417
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Study on the development of nanotechnology in advanced countries and in Brazil BJPS
Rediguieri,Carolina Fracalossi.
The study shows how nanotechnology evolves in developed countries and Brazil, raising aspects of private and governmental initiatives. The investigation was based in scientific literature, electronic articles and conference reports. Several sources of literature were used, including electronic databases and reference lists. By this study, it was observed that, although nanotechnology is in initial stage of development all over the world, the developed countries have had growing public and private investments in the area each year. In those countries, there is a concern toward both, the formation of specialists in nanotechnology and the transference of technology developed in universities and research institutes to industry. In Brazil, the study showed that...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nanotechnology/development; Nanobiotechnology; Nanopharmaceutical.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000200002
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